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  Indian J Med Microbiol
 

Figure 1: Activated platelets present highly effi cacious surfaces for plasma coagulation, according to the cell-based model, resulting in the thrombin burst. As a result of the thrombin burst, fi brinogen is converted into fi brin and factor XIII (FXIII) is activated. The activated FXIII (FXIIIa) crosslinks the initially soluble fi brin monomers into an insoluble fi brin strand.

Figure 1: Activated platelets present highly effi cacious surfaces for plasma coagulation, according to the cell-based model, resulting in the thrombin burst. As a result of the thrombin burst, fi brinogen is converted into fi brin and factor XIII (FXIII) is activated. The activated FXIII (FXIIIa) crosslinks the initially soluble fi brin monomers into an insoluble fi brin strand.